James Lee Selected Research

Olmesartan Medoxomil (Votum)

4/2016	A thorough QTc study demonstrates that olmesartan medoxomil does not prolong the QTc interval.
1/2014	Triple-combination treatment with olmesartan medoxomil/amlodipine/ hydrochlorothiazide in Hispanic/Latino patients with hypertension: the TRINITY study.
7/2013	Combined olmesartan, amlodipine, and hydrochlorothiazide therapy in randomized patients with hypertension: a subgroup analysis of the TRINITY study by age.
3/2012	Efficacy and safety of triple-combination therapy with olmesartan, amlodipine, and hydrochlorothiazide in study participants with hypertension and diabetes: a subpopulation analysis of the TRINITY study.
3/2012	Long-term efficacy and safety of triple-combination therapy with olmesartan medoxomil and amlodipine besylate and hydrochlorothiazide for hypertension.
12/2011	24-hour efficacy and safety of Triple-Combination Therapy With Olmesartan, Amlodipine, and Hydrochlorothiazide: the TRINITY ambulatory blood pressure substudy.
7/2010	Triple therapy with olmesartan medoxomil, amlodipine besylate, and hydrochlorothiazide in adult patients with hypertension: The TRINITY multicenter, randomized, double-blind, 12-week, parallel-group study.
11/2009	Subgroup analyses of an efficacy and safety study of concomitant administration of amlodipine besylate and olmesartan medoxomil: evaluation by baseline hypertension stage and prior antihypertensive medication use.
9/2009	Efficacy and safety of long-term treatment with the combination of amlodipine besylate and olmesartan medoxomil in patients with hypertension.
4/2008	The combination of olmesartan medoxomil and amlodipine besylate in controlling high blood pressure: COACH, a randomized, double-blind, placebo-controlled, 8-week factorial efficacy and safety study.

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James Lee Research Topics

Disease

23	Neoplasms (Cancer) 01/2021 - 10/2003
15	Hypertension (High Blood Pressure) 11/2018 - 03/2008
7	Inflammation (Inflammations) 01/2018 - 08/2006
6	Infections 01/2020 - 12/2005
5	Hemorrhage 01/2022 - 01/2014
4	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2019 - 08/2013
4	Wounds and Injuries (Trauma) 01/2019 - 05/2004
4	Primary Graft Dysfunction 01/2012 - 11/2010
3	Fibrosis (Cirrhosis) 01/2022 - 11/2006
3	Myocardial Infarction 01/2022 - 06/2008
3	Stroke (Strokes) 01/2022 - 01/2015
3	Atrial Fibrillation 08/2021 - 01/2015
3	Atopic Dermatitis (Atopic Eczema) 12/2018 - 10/2017
3	Idiopathic Pulmonary Fibrosis 03/2016 - 04/2011
3	Lung Injury 08/2013 - 11/2006
3	Colorectal Neoplasms (Colorectal Cancer) 12/2012 - 09/2003
3	Chronic Renal Insufficiency 10/2012 - 01/2006
3	Breast Neoplasms (Breast Cancer) 04/2009 - 08/2006
3	Glioma (Gliomas) 04/2009 - 05/2005
3	Adenoma (Adenomas) 03/2008 - 08/2006
2	Migraine Disorders (Migraine) 12/2021 - 04/2007
2	Aortic Valve Stenosis (Aortic Stenosis) 11/2021 - 01/2021
2	Anemia 05/2021 - 05/2019
2	Obstructive Sleep Apnea 01/2021 - 03/2014
2	Neuralgia (Stump Neuralgia) 01/2019 - 10/2018
2	Neoplasm Metastasis (Metastasis) 07/2017 - 04/2007
2	Type 2 Diabetes Mellitus (MODY) 04/2016 - 10/2015
2	Diabetes Mellitus 06/2015 - 08/2012
2	Aneurysm (Aneurysms) 05/2015 - 06/2002
2	Rupture 05/2015 - 01/2014
2	Lung Neoplasms (Lung Cancer) 01/2015 - 04/2010
2	Carcinoma (Carcinomatosis) 01/2015 - 10/2012
2	Coronary Artery Disease (Coronary Atherosclerosis) 07/2013 - 06/2008
2	Renal Insufficiency (Renal Failure) 07/2013 - 05/2008
2	Chronic Obstructive Pulmonary Disease (COPD) 01/2012 - 01/2009
2	Acute Lung Injury 11/2011 - 11/2010
2	Papillary Thyroid Cancer 06/2010 - 04/2007
2	Colonic Neoplasms (Colon Cancer) 09/2009 - 09/2003
2	Hyperaldosteronism (Conn Syndrome) 03/2008 - 01/2008
2	Pulmonary Fibrosis (Fibrosing Alveolitis) 04/2007 - 11/2006
2	Rectal Neoplasms (Rectal Cancer) 03/2005 - 09/2003
1	Postoperative Pain 08/2022
1	Inguinal Hernia (Direct Inguinal Hernia) 08/2022
1	Ventral Hernia 07/2022
1	Cardiogenic Shock 03/2022
1	Aortic Valve Insufficiency (Aortic Regurgitation) 03/2022
1	Primary Hyperparathyroidism 03/2022
1	Hydronephrosis 01/2022

Drug/Important Bio-Agent (IBA)

14	Proteins (Proteins, Gene)FDA Link 11/2020 - 05/2004
13	Amlodipine (Norvasc)FDA LinkGeneric 01/2014 - 04/2008
10	Olmesartan Medoxomil (Votum)FDA Link 04/2016 - 04/2008
9	Hydrochlorothiazide (Esidrix)FDA LinkGeneric 01/2014 - 07/2010
6	olmesartanIBA 08/2013 - 07/2008
6	Antihypertensive Agents (Antihypertensives)IBA 07/2013 - 03/2008
5	Biomarkers (Surrogate Marker)IBA 11/2020 - 11/2006
5	CytokinesIBA 10/2017 - 10/2010
4	Warfarin (Coumadin)FDA LinkGeneric 05/2021 - 01/2014
3	EnzymesIBA 01/2022 - 05/2011
3	Prostaglandins DIBA 01/2012 - 11/2010
2	Type A Botulinum Toxins (Botox)FDA Link 12/2021 - 10/2018
2	Glucose (Dextrose)FDA LinkGeneric 11/2020 - 03/2005
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2020 - 01/2012
2	CollagenIBA 01/2020 - 05/2011
2	Messenger RNA (mRNA)IBA 01/2020 - 05/2011
2	Interleukin-17 (Interleukin 17)IBA 01/2019 - 01/2018
2	AntibodiesIBA 01/2018 - 01/2018
2	Biological ProductsIBA 10/2017 - 04/2009
2	Imiquimod (Aldara)FDA LinkGeneric 10/2017 - 01/2007
2	Transcription Factors (Transcription Factor)IBA 01/2016 - 09/2008
2	Protein Isoforms (Isoforms)IBA 01/2016 - 04/2010
2	AnticoagulantsIBA 06/2015 - 01/2015
2	Pharmaceutical PreparationsIBA 05/2015 - 05/2012
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2014 - 06/2008
2	Cetuximab (Erbitux)FDA Link 12/2012 - 10/2012
2	Hydroxyproline (4 Hydroxyproline)IBA 05/2011 - 11/2006
2	AST 120IBA 03/2006 - 01/2006
1	Ropivacaine (Naropin)FDA LinkGeneric 08/2022
1	Extracellular Matrix ProteinsIBA 01/2022
1	VaccinesIBA 01/2022

Therapy/Procedure

24	Therapeutics 12/2021 - 06/2005
8	Lung Transplantation 01/2018 - 04/2007
4	Adrenalectomy 05/2008 - 08/2006
3	Transcatheter Aortic Valve Replacement 11/2021 - 01/2021
3	Transplantation 01/2018 - 11/2011
3	Drug Therapy (Chemotherapy) 05/2015 - 10/2012
2	Punctures 01/2022 - 01/2020
2	Continuous Positive Airway Pressure 01/2021 - 03/2014
2	Catheters 01/2020 - 04/2018
2	Surgical Amputation (Amputations) 01/2019 - 10/2018
2	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 11/2018 - 06/2015
2	Radiotherapy 03/2016 - 07/2006
2	Intensity-Modulated Radiotherapy (Radiotherapy, Intensity Modulated) 03/2016 - 12/2009
2	Aftercare (After-Treatment) 01/2014 - 01/2007
2	Ambulatory Care (Outpatient Care) 07/2013 - 12/2006
1	Local Anesthesia 08/2022
1	Analgesia 08/2022
1	Surgical Mesh 07/2022
1	Extracorporeal Membrane Oxygenation 03/2022
1	Bioprosthesis 03/2022
1	Parathyroidectomy 03/2022